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Stinky Frogs Are a Treasure Trove of Antibiotic Substances
4 years ago

ScienceDaily (Nov. 30, 2011) Some of the nastiest smelling creatures on Earth have skin that produces the greatest known variety of anti-bacterial substances that hold promise for becoming new weapons in the battle against antibiotic-resistant infections, scientists are reporting. Their research on amphibians so smelly (like rotten fish, for instance) that scientists term them "odorous frogs" appears in ACS' Journal of Proteome Research.


Yun Zhang, Wen-Hui Lee and Xinwang Yang explain that scientists long have recognized frogs' skin as a rich potential source of new antibiotics. Frogs live in warm, wet places where bacteria thrive and have adapted skin that secretes chemicals, known as peptides, to protect themselves from infections. Zhang's group wanted to identify the specific antimicrobial peptides (AMPs), and the most potent to give scientists clues for developing new antibiotics.


They identified more than 700 of these substances from nine species of odorous frogs and concluded that the AMPs account for almost one-third of all AMPs found in the world, the greatest known diversity of these germ-killing chemicals. Interestingly, some of the AMPs have a dual action, killing bacteria directly and also activating the immune system to assist in the battle.


The authors acknowledge funding from the National Basic Research Program of China and The National Natural Science Foundation of China.


no pain
4 years ago

no's always something nasty,that has all the best bacteria fighting superpowers.

This post was modified from its original form on 14 Dec, 7:14
4 years ago

Thanks for Posting this Important info. I seen this on the Nat'l. Geo Channel about the wonders of many Insects and Amphibians for Medicine. I just hope they don't hurt the little fellows when they Harvest them. At Job center because of Storms, might not be back till tomorrow.

4 years ago

There goes more frogs into the research labs. There are plenty of plants that stink to high heaven. Why don't they try using them instead of innocent little frogs? I hate the thought of animals giving their lives for us! Thanx Teresa.

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