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myasthenia gravis
Dec 6, 2006


Severe muscle weakness becomes increasingly more common in recent times. The classical disease with severe muscle weakness is myasthenia gravis or M.G. It is most common in young women, although it may develop at any age and in both sexes. Males are more affected in their later decades of life. Certain muscles become chronically weak and easily fatigued. Most affected are the muscles of the head and neck, later progressively also the muscles of the chest and limbs. The first sign of myasthenia gravis is usually a drooping eyelid (ptosis). Frequently double vision (diplopia) develops as the disease progresses, also difficulty chewing or swallowing or even breathing. The speech may be slurred and the vision blurred. Usually the condition becomes worse as the day progresses. In medical treatment a group of drugs, called anticholinesterases, is used, such as neostigmine or pyridostigmine. These delay the normal inactivation of the neurotransmitter acetylcholine, which results in a temporary improvement in muscle functions. Frequently the thymus gland is greatly enlarged and may be surgically removed. This can result in some medium-term improvement in one-third of cases. There are frequent side effects from drug therapy, such as abdominal cramps, diarrhoea, nausea, vomiting, excessive mucus formation, bronchial spasms, twitching of face muscles, spasms and freezing of muscles, tremors, incoordination and paralysis. It is easy to overdose with a resulting 'cholinergic' crisis often resulting in death.

please help the myasthenia gravis association of barbados  thank you
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Posted: Wednesday December 6, 2006, 12:36 pm
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kayla james
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female, age 27, single
Barbados, West Indies, Barbados
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Dec
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Severe muscle weakness becomes increasingly more common in recent times. The classical disease with severe muscle weakness is myasthenia gravis or M.G. It is most common in young women, although it may develop at any age and in both sexes. Males are m...


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