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Sep 4, 2008

Tucson, Arizona | Published: 11.28.2007 advertisement <a href="http://gcirm.tucson.gcion.com/RealMedia/ads/click_lx.ads/news.azstarnet.com/stories/local/1946403664/300x250_1/OasDefault/Bedmart/bedmart.html/34653961313038623438633030653330?http://www.azbedmart.com/index_files/Page1038.htm"><IMG SRC="http://gcirm.tucson.gcion.com/RealMedia/ads/Creatives/OasDefault/Bedmart/bedmart.jpg" WIDTH=300 HEIGHT=250 BORDER=0></a> A top scientist using stem cells from human embryos to cure disease and repair injuries will proceed with his work, he said in Tucson on Tuesday, despite a recent breakthrough showing the controversial embryos may no longer be needed. That blockbuster breakthrough was announced last week by researchers in Wisconsin and Japan, who have discovered how to genetically program human skin cells to behave like embryonic stem cells. That means the skin cells can develop into any cell in the human body — in the brain, heart, liver, muscle or bones — where they potentially can be used for lifesaving repairs or cures. Until now, only stem cells from human embryos — each a potential human life — could do that. But scientists deeply involved in human embryonic stem-cell research are unlikely to scrap years of work, however controversial, to start over with the new skin-cell technology, said one noted for cutting-edge achievements in this field. "I do think a great deal of this work could be done with the skin-cell-derived stem cells. But we'd have to start completely over, from scratch, and we are not going to slow down to do that, not at this point," said Hans Keirstead, a neurobiologist and stem-cell researcher at the University of California-Irvine. Speaking at University Medical Center, Keirstead outlined his progress, which has taken off in the past three years — after California sidestepped President Bush's ban on federal funding for research using human embryos. In 2004, California voters overwhelmingly passed Proposition 71, allocating $3 billion in state funds to develop new embryonic stem-cell lines, attracting some of the best and the brightest researchers in the world to relocate there. Since then, Keirstead and his team at the Reeve-Irvine Research Center (named for the late actor Christopher Reeve, who suffered a devastating spinal-cord injury) have used these new stem-cell lines to restore full mobility to rats paralyzed by spinal cord injuries. To do that, he had to find a way to purify and differentiate human embryonic stem cells to develop into a type of nervous-system cell needed to restore spinal cell function. He is using similar techniques to transform embryonic cells into motor neurons to restore muscle function. These breakthroughs have created a blueprint that can be used to create cells to replace those damaged by such human scourges as multiple sclerosis, Parkinson's disease, heart disease, stroke, ulcerative colitis, muscle atrophy in newborns, Lou Gehrig's disease and diabetes. Embryonic stem cells — taken from 5-day-old embryos discarded by fertility clinics — "have the potential to address every single human disorder," Keirstead said. "They are the greatest single scientific advance in human history, with the potential to develop into any kind of cell in the human body." Keirstead's work is expected to set the stage for the first human clinical trial in the world using embryonic stem cells, possibly as early as next year. Only 40 years old, Keirstead is as passionate about defending the use of human embryos for this purpose as he is for the work itself. "The ethical controversy starts with the fact that if the embryo were implanted in the uterus, it would develop into a human," he said. "But these embryos were destined to be destroyed. "It is my personal feeling it's a very ethical decision to use this tissue to end human suffering, to better human life, than to destroy it. "If you think this is a divine entity with tremendous spiritual value, I don't disagree with you. I value them no less." Keirstead's unwillingness to abandon progress in embryonic stem-cell research, to begin again with non-controversial human skin cells, actually is shared by the skin-cell researchers at the University of Wisconsin. They've warned that work with embryonic stem cells must continue, that their research remains in its early stages and that comparison studies must be done to ensure the genetically engineered skin cells do not behave in unexpected ways. There also are concerns that the techniques used might disrupt human DNA and trigger cancer in patients — questions that must be answered before they can be approved for human experiments.

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Posted: Thursday September 4, 2008, 9:39 am
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Elitsa Borisova
female, age 33, single
Dublin, 15, Ireland
ELITSA'S SHARES
Feb
8
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\nDear patients,instead of writing my own comments to prove how effective stem cell transplants can be, I prefer to let you see the information below and estimate whether it worths or not. Here are some facts:http://vimeo.com/us er290654/videoshttp://ww. ..
Sep
21
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http://www.youtube.com/wa tch?v=ZMbnkVw-tf4&fea ture=related
Sep
3
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\nBreakout Session 3: Hans Keirstead\r\nPo sted by katewill on April 13, 2008\r\n\r\n\r\nHe says that in his lab they focus on acute, sub-acute, and chronic.  (Hans Keirstead, for those who haven’t met him, is kind of Robert Redford type.  ...


SHARES FROM ELITSA'S NETWORK
Mar
31
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\\nZEN was suspended by Eric with no warning. We don\\\'t know any reasons nor how long it will last....\\r\\nI asked about it on the forum but my post was immediately deleted. 2 threads and petitions about Zen also. And 2 her help-groups. :-(\\r\\nUntill to...
Feb
18
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\\n\\r\\nHello my C2 Family, \\r\\nFirst let me say Thank You to those of you who have so sweetly fwd my posts. You are SO AWESOME!! I will never forget your help. Anytime I can repay the favour, please tell me. Second, my Submit button has disappeared lea...
Nov
18
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\\n\\\'\\\'It is horrifying that we have to fight our own government to save the environment.\\\"\\r\\n-An sel Adams photographer\\n
Nov
17
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\\nThe HORD has begun its own orphanage Primary School in March 2010 in the rural Bussiwa village in kamuli district.  People live in small grass hatched houses, often large families in one room.  The people who live in these rural villages a...
Oct
17
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\\nHELP orphans in Uganda !!!\\r\\n WHAT DO THESE KIDS EXPECT FROM THE WORLD ??!!! What can a helpless child under the age of 12 expect from his lonesome world, other than food, proper sleep, non-ragged cloths and quest for knowledge?... Also when the n...


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