New Vaccine Takes the Fun Out of Cocaine

Most of us are used to thinking of vaccines as a preventative treatment for bacterial and viral diseases — you expose the immune system to a dead or weakened version of the disease, and your body learns how to fight it off in the future. It turns out you can use vaccines to train the body to fight off all sorts of things, including drugs like cocaine.

The way the cocaine vaccine works is by combining norcocaine, a drug very similar to cocaine, with an inactivated common cold virus. When the immune system tries to fight off the virus, it creates antibodies to the virus and to the drug. Then, if someone who’s received the vaccine in the past tries to abuse the drug, their body attacks the cocaine and destroys it before it can reach the brain and have any mind-altering effects.

So far, the vaccine has worked well in lab rats and non-human primates, both lowering the amount of cocaine in the blood directly after receiving a dose, and resulting in animals who seem to be less likely to develop an addiction in the first place. The results have been so promising that one study is on its way to human clinical trials.

It’s not yet clear exactly how long the effects would last in humans, as the vaccine has only been shown to remain effective for about 13 weeks in mice and 7 weeks in primates. It’s possible addicts in recovery would need booster shots every few weeks.

The vaccine is a promising treatment option for narcotics addicts who just can’t kick their drug habit — currently, there are very few effective medical treatments for treating addiction. But what if doctors or policymakers decide to require the vaccine be given to populations that are merely “at risk” for developing an addiction?

Is it ethical to inject children or teens with the vaccine to prevent them from potentially abusing hard drugs in the future? Would it be ethical to force pregnant addicts to take the vaccine to protect their unborn children from developmental problems or birth defects? Will we require welfare recipients to take the vaccine? Will health insurance cover the cost?

The vaccine also isn’t without risks for cocaine addicts. People who already know what kind of high to expect from cocaine might try to compensate for the diminished effects by simply taking larger doses of the drug — potentially resulting in overdose.

At the moment, researchers are also working on vaccines for other drugs, including methamphetamine, heroin and nicotine, which work in a similar way. As these vaccines get closer and closer to approval, the American public is going to have to start asking some tough questions about addiction and free will.

Photo credits: Thinkstock

115 comments

Oleg Kobetz
Oleg Kobetz2 years ago

Thank you

Troy Grant
Troy Grant2 years ago

Getting rid of natural drugs simply means that people will take more dangerous unnatural drugs from Big Pharma.

LMj Sunshine

Thank you.

LMj Sunshine

Interesting info.

LMj Sunshine

Interesting info.

Casey Richardson
Casey Stewart3 years ago

It's so amazing how everything they're developing "cures" for has, either zero natural ingredients or a minuscule amount. It's all based on their developed chemicals that come with 100+ side effects usually. Everyone's finally coming to their senses about how ridiculous cannabis prohibition was. It's been scientifically proven (check yourself) to fight cancer cells. It has 2 side effects, a mellowing buzz and munchies. Imagine the trees and money alone that we could save using hemp instead. Not to mention the other long (possibly endless) list of benefits cannabis can give us. It's benefits, hands down, cancel out it's supposed risks. Thank goodness our generation has started making sense able decisions concerning our planet. Maybe one day, with enough luck & sense ability, future generations of ours will successfully and entirely leave zero carbon footprints. To benefit Earth fully. That is, if mother nature has enough pitty left to allow us a chance.

Donna Ferguson
Donna F.3 years ago

I read what others had to say, but I think the research on a "hard drugs vaccine" might be useful. We'd sure have a different society if nobody got anything out of hard drugs.

Fi T.
Fi T.3 years ago

Money isn't everything

Angela Ray
Angela Ray3 years ago

Wow. There are so many things doctors don't want people to know. Ignorance = profit!!

Monika Ka
Monika K.3 years ago

I'm just waiting for the day when someone will discover a cure for the cancer from the ingredients in grass.