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Researchers Find Key Pathways for Two Deadly Cancers - BRAIN & PANCREATIC


Health & Wellness  (tags: USA. medical research, cancers, brain cancer, pancreatic cancer, genetics, genetic clusters )

K. A.
- 2153 days ago - cnn.com
Typical pancreatic cancer had 63 genetic changes; average brain tumor had 60; Clusters of seemingly unrelated genes work along same pathways to create cancer; New genetic maps include mutated, missing, extra, over- and underactive genes; new treatments!



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Comments

K. A. Hilliker (293)
Friday September 5, 2008, 3:37 pm
Friday's research also found that clusters of seemingly disparate genes all work along the same pathways. So instead of today's hunt for drugs that target a single gene, the idea is to target entire pathways that most patients share. Think of delivering the mail to a single box at the end of the cul-de-sac instead of at every doorstep. The three studies, published in the journals Science and Nature, mark a milestone in cancer genetics.

"This is the next wave," said Dr. Phillip Febbo of Duke University's Institute for Genome Sciences and Policy, who was not involved with the new research. "What's really important is that finding those common elements within the landscape suggests there are therapeutic interventions that can help the whole group."


 
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