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Do Soybeans Really Offer HIV Resistance?

Do Soybeans Really Offer HIV Resistance?

Could the humble soybean really provide us with a new and more effective HIV inhibitor that comes without the drug resistance problems found in current therapies?

Researchers at the George Mason-based National Center for Biodefense and Infectious Diseases and the Department of Molecular and Microbiologyhave found that there is potential if further tests on genistein, a compound derived from soybeans and other plants, continue to show positive results.

“Instead of directly acting on the virus, genistein interferes with the cellular processes that are necessary for the virus to infect cells,”said lead researcher Yuntao Wu. “Thus, it makes the virus more difficult to become resistant to the drug. Our study is currently in its early stage. If clinically proven effective, genistein may be used as a complement treatment for HIV infection.”

HIV hijacks the surface sensors of our cells in order to replicate itself. Genistein, the compound derived from soybeans, is known as a “tyrosine kinase inhibitor.” That means it can block communication from a cell’s surface sensors to a cell’s interior. As such, it would retard HIV infiltration and proliferation in the body, effectively hampering the virus from spreading.

As mentioned above, genistein may have other benefits too. Due to the fact that it is a plant-based compound, it has the potential to offer a HIV treatment that could sidestep what is known as drug toxicity.

Many HIV patients are forced to take a combination of several drugs in order to stop HIV advancing in their bodies. As a result, HIV sufferers may become ill as a result of their daily regimen of drugs.

In addition to this, there is also the fact that HIV can mutate and become resistant to the drugs a sufferer is currently using.Genistein potentially would not be subject to such constraints or offer the toxicity side effects of other drugs.

Now, this isn’t the first time that the soybean compound has been eyed as a potential contender for a new wave of HIV treatments. Researchers have known of soybean’s potential HIV inhibiting properties sinceat least 2008, and a2011 Chinese study investigated the potential of the mini-black soybean as a protease inhibitor that, again, could slow HIV spread in the body.

Soybeans have also been found to contain the potential for anti-cancer drugs, thoughextracting the precise compounds for refinement has been difficult.

Sadly though, it seems unlikely that a daily diet of genistein-rich food such as soybeans could, on its own, provide sufficient concentrations of the compound to offer HIV resistance.

“Although genistein is rich in several plants such as soybeans, it is still uncertain whether the amount of genistein we consume from eating soy is sufficient to inhibit HIV,” Wu is quoted as saying.

Wu and team are now attempting to research exactly the amounts that would be needed to offer health benefits and whether refining a drug treatment based on the compound will be viable. Alternatively, it may be that soybeans and other genistein-rich plants could be engineered to offer greater concentrations of genistein but, of course, this comes with its own set of limiting factors, not least of which is the potential wider environmental impact.

With an eye to the viability of treatment, genistein would never be a stand-alone HIV inhibitor, and certainly not an HIV cure.

What it does have the potential to be, however, is an inexpensive HIV inhibitor that might come with fewer medical issues than the current, harsh variety of drug treatments.

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6:21PM PDT on Jun 4, 2014

noted

6:11PM PDT on Jun 4, 2014

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8:07PM PDT on Mar 13, 2014

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5:16AM PST on Feb 19, 2014

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Kind Regards

1:42PM PST on Feb 18, 2014

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7:11PM PST on Feb 1, 2014

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3:45PM PST on Jan 24, 2014

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5:42PM PST on Jan 10, 2014

i am RODA by name, i want to tell the whole world how i got my hiv cured, i live in Manchester united kingdom, presently i am working as a teacher in an high school, i was once a stripper in a club and i got affected with HIV due to the nature of my job, in February 2nd 2009, This is not design to convince you but its just a personal health experience.
I never taught doctor LAWCY could ever get my HIV-AIDS cured with his healing herb spell, i have been spending so much buying my drugs for the past three years now and taking several medication but no relieve, until one day i was just browsing on the internet when i came across a great post of MARIAN, who explained to me how a great dr called PAPA LAWCY helped her, by curing her from HIV, i thought as much and i quicklly contacted him, and he gave to me the assurance that he is going to help me with his herbs, he told me to buy the herbs which he will use for the preparation of my medicine which i did, he prepared the medicine and told me how i am going to take them which i did, just three days later i went to the hospital to give the final test and the doctor confirm that i am now negative, i am so happy that GOD sent DR LAWCY to help me out of my problems, if you are out there passing through this kind of problem, you can also contact him on DRLAWCYSPELLHOME@GMAIL.COM.com, and i pray that he will help you also.
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8:09AM PST on Dec 27, 2013

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2:14AM PST on Nov 19, 2013

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