6. Arctic National Wildlife Refuge, Alaska
You’d be hard-pressed to find a place more remote — and more difficult to get to — than the Arctic National Wildlife Refuge in far northeastern Alaska. Nearly twice the size of Massachusetts, there are no roads within or leading to the refuge. Most visitors — all 1,500 of them each year — arrive by aircraft. Though there are a handful of tiny villages, most of the noise comes from the area’s vibrant wildlife: polar bears, caribou, and wolves, just to name a few.