The platelets in the plaque take in HDL A1 cholesterol and they won’t take anything else… They take in sulfate, and they produce cholesterol sulfate in the plaque.
The sulfate actually comes from homocysteine. Elevated homocysteine is another risk factor for heart disease. Homocysteine is a source of sulfate. It also involves hemoglobin. You have to consume energy to produce a sulfate from homocysteine, and the red blood cells actually supply the ATP to the plaque.
So everything is there and the intent is to produce cholesterol sulfate and it’s done in the arteries feeding the heart, because it’s the heart that needs the cholesterol sulfate. If [cholesterol sulfate is not produced]… you end up with heart failure.”
So, in a nutshell, high LDL appears to be a sign of cholesterol sulfate deficiency—it’s your body’s way of trying to maintain the correct balance by taking damaged LDL and turning it into plaque, within which the blood platelets produce the cholesterol sulfate your heart and brain needs for optimal function. What this also means is that when you artificially lower your cholesterol with a statin drug, which effectively reduces that plaque but doesn’t address the root problem, your body is not able to compensate any longer, and as a result of lack of cholesterol sulfate you may end up with heart failure.
IMPORTANT UPDATE: How Sun Exposure Impacts Your Sulfur Status
According to the conventional view, high LDL is correlated with heart disease, so the idea is that you can take a statin drug to artificially reduce the LDL and you’ll be fine. However, as Dr. Seneff explains, if you have high LDL, it’s because your body probably needs it to produce cholesterol sulfate, which your heart requires for optimal function. Hence, when you simply remove the LDL, you also remove your body’s “backup” mechanism to keep your heart as healthy as possible, and as a result you get heart failure.