Effect of Coffee on Alzheimer’s

An unidentified component of coffee interacts with the caffeine, which could be the reason that coffee drinking protects against Alzheimer’s disease. A recent Alzheimer’s study by scientists at the University of South Florida found that this interaction boosts blood levels of a growth factor called GCSF (granulocyte colony stimulating factor) that seems to fight off the Alzheimer’s disease process. Hurray for coffee!

The findings appear in the online version of an article in the Journal of Alzheimer’s Disease. The USF team presents the first evidence that caffeinated coffee offers protection against the disease, protection that doesn’t occur with other caffeinated drinks or decaffeinated coffee.

The new study shows that caffeinated coffee induces an increase in blood levels of GCSF, a substance that is found to be greatly diminished in patients with Alzheimer’s disease–and demonstrated to improve memory in Alzheimer’s studies. A just-completed clinical trial at the USF Health Byrd Alzheimer’s Institute is looking into GCSF treatment to prevent full-blown Alzheimer’s in patients with mild cognitive impairment. The results of that trial are now being evaluated and will be published soon.

The researchers are hoping to identify this yet unknown component so that it can be used to provide long-term protection against Alzheimer’s.


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Marianne B.
MARIA B.3 years ago

Sorry, too confusing. One article says coffee is good for this and that, another says coffee causes this and that health problems. Do they say how much to drink? never...or decaf coffee? I wish they and (who are they) ? would make up my mind..all these studies cost money, in my estimate wasted on more necessary studies.

Kim C.
Kim C.3 years ago

A much better rticle than the last article about coffee I read. 7 reasons to cut back on coffee.
If you are worried about the devistation growing coffee can have, there are companies that do harvest socially and environmetally responisble coffee. www.thanksgivingcoffee.com is one of those companys.

My father died from Azhiemers. They said the cause was from a head injury when he was teen. He fell off a ladder. I am guessing the injury was similar to football head injuries.
The Alzheimers showed up before he was 60. He had to take an early retirement because he could no longer do his job correctly. He was a fingerint examiner before computers took over.

Danuta Watola
Danuta Watola3 years ago

Thank for the informative article!

Michael Wecke
Michael Wecke3 years ago

Enjoy with some chocolate! Better would be dark chocolate - but it's an acquired taste.

Richelle Rausch
Richelle Rausch3 years ago

Everyone I knew with Alzheimer's drank caffeinated coffee everyday....??????

Lakmal Wijerathna

Thank you. Be aware about Green teafor a healthy life.

Danielle I.
Danielle I.3 years ago

Yay! I love finding out good things about some of the not so good things that I love :)

Diana W.
Diana W.3 years ago

Very cool! Way to go, USF!

Waltraud U.
Waltraud U.3 years ago

Good, very good. - Thank you.

Susy L.
Susy L.3 years ago

Interesting, my dad had Alzheimer's and wasn't a coffee drinker...hmmmm.