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Scientists Discover How Cannabis Slows Alzheimer's Disease

Health & Wellness  (tags: AlternativeMed, Body-Mind-Spirit, cancer, death, diet, disease, drugs, environment, family, food, government, healthcare, illness, investigation, medicine, prevention, protection, POT, research, safety, society, study, treatment )

- 1737 days ago -
Researchers at the Roskamp Institute in Florida have shown for the first time how cannabinoids - the active chemicals in marijuana - are able to reduce the build-up of a key indicator of Alzheimer's disease.

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Kit B (276)
Thursday August 22, 2013, 10:54 am
Photo Credit: The AD Plan - Photo description - Clumps of protein known as beta-amyloid plaque are a key trait of Alzheimer’s and contribute to the progression and symptoms of the disease. New evidence points to a unique role of marijuana in removing this plaque from the brain.

Previous studies suggest a role of cannabis in slowing the progression of Alzheimer’s and now scientists can explain why.

Researchers at the Roskamp Institute in Florida have shown for the first time how cannabinoids – the active chemicals in marijuana – are able to reduce the build-up of a key indicator of Alzheimer’s disease.

For long, scientists have linked the loss of cell and brain tissue in Alzheimer’s to abnormal structures called beta-amyloid (Aβ) plaque. Levels of plaque in a patient’s brain can even predict the severity of symptoms and tissue damage suffered.

Published last week in the Molecular and Cellular Neuroscience journal, the new findings reveal how cannabinoids reverse the build-up of plaque in Alzheimer’s by expelling it from the brain.

(MORE: Can Marijuana Help Combat Brain Aging?)

The team, led by Corbin Bachmeier, Ph.D, explains that Alzheimer’s is not a result of abnormal production of the plaque, but “the result of impaired Aβ clearance from the brain.”

Their results suggest that chemicals in marijuana can aid the plaque in crossing the blood-brain barrier, a process that allows plaque levels to be kept low in healthy people. Previous studies show that this process is blocked in patients with Alzheimer’s disease.

While this study was the first to identify this unique function of cannabinoids, it confirms the results of prior research linking the chemicals to a reduction in both plaque levels and Alzheimer’s symptoms.

What’s more, others suggest cannabinoids have a variety of effects that could be helpful in treating the disorder.

Earlier this year, Tim Karl, Ph.D, a senior investigator at Neuroscience Research Australia who was not involved with the current study, found that mice with Alzheimer’s experienced dramatic improvements in memory after treatment with cannabidiol (CBD).

CBD is one of over 60 cannabinoids found in marijuana and has captured the attention of researchers due to its lack of psychoactive effects.

“It basically brings the performance of the animals back to the level of healthy animals,” Karl told Sydney Morning Herald.

“You could say it cured them, but we will have to go back and look at their brains to be sure.”

Earlier studies point to the anti-inflammatory properties of cannabinoids as useful in Alzheimer’s.

Gary Wenk, Ph.D, a professor of neuroscience, immunology and medical genetics at Ohio State University, was one of the first scientists to suggest this.

“I’ve been trying to find a drug that will reduce brain inflammation and restore cognitive function in rats for over 25 years; cannabinoids are the first and only class of drugs that have ever been effective,” he told Time Magazine.

He believes that stigma still hinders marijuana-based medicine from being widely accepted, but is hopeful that things will change.

“I think that the perception about this drug is changing and in the future people will be less fearful.”

Alzheimer’s disease continues to be a leading cause of disability among the growing population of seniors. Without a breakthrough in treatment, the number of Alzheimer’s cases are expected to triple over the next 50 years.

Truth on -


Barbara K (60)
Thursday August 22, 2013, 11:32 am
Thank you, my friend for the info. Wouldn't it be wonderful if this all works out that one plant can cure or help with these awful diseases? I'll need to really look into it, as I've never tried the stuff.

Kit B (276)
Thursday August 22, 2013, 11:34 am

Barbara, most people don't know this. This is just the tip of the research out there.

JL A (281)
Thursday August 22, 2013, 11:49 am
Important research to pay attention to--thanks Kit!

Arielle S (313)
Thursday August 22, 2013, 11:54 am
But if this did so much good for so many things, why would we need all those hospitals and drugs...? Oh.... MRI costs more than a little pot....

Kit B (276)
Thursday August 22, 2013, 11:57 am

Yeah, how about that, Arielle. Okay, maybe they need tests to figure out what is wrong, but until the doctor's look at the research that has been done, see the startling results for so many and finally give their approval things will remain stagnate. Almost anything costs more then pot.

Sheila D (194)
Thursday August 22, 2013, 12:08 pm
So happy to be back...thanks for these articles showing the medical benefits of maijuana.
Though can't currently give you a star...later.

Joanne D (38)
Thursday August 22, 2013, 12:24 pm
I have just been able to post 2 comments without getting a 500 error. First time in 2 days. Those of us having problems may want to try.

On topic - yes, sometimes tests are needed, but I am not sure anything is really better than empirical evidence. Particularly since there is no remedy, no matter how simple, that works for 100% of people 100% of the time. People are different, not only from each other, but from themselves at a different time. Which is why I would love for us to quit the war on marijuana.

It is also why I mourn the loss of many things which have always worked for em but which no one can get any more.

Vallee R (280)
Thursday August 22, 2013, 2:06 pm
Joanne - I am posting here too - amazing! 'theres no reaso that marijuana should be banned - except - oh - it might help us!

Nancy M (197)
Thursday August 22, 2013, 2:16 pm

S S (0)
Thursday August 22, 2013, 2:24 pm
Thank you.

Bryna Pizzo (139)
Thursday August 22, 2013, 3:39 pm
Thank you so very much for the exciting news. I wish we could get it for our step mother. Watching her slowly slip away is excruciating. (n, p, t)

I can't believe we can post again. Hooray!

Yvonne White (229)
Thursday August 22, 2013, 4:03 pm
"CBD is one of over 60 cannabinoids found in marijuana and has captured the attention of researchers due to its lack of psychoactive effects." So no high, just smarter old people..hmm, I think they better use the Whole plant if they want to keep us in the nursing homes!;) I read a Sci-Fi short story once about John Lennon in a nursing home in the was cool, totally wrong, but still cool..I think the government will HAVE to legalize pot Very Soon if us Boomers start getting rowdy! "Another One Bites the Dust" at full blast will freak out the Nursing Home owners!;)


Lois Jordan (63)
Thursday August 22, 2013, 4:21 pm
So glad to see these articles now...thanks, Kit.
And, Yvonne, I am nearly on the floor laughing at your comment above! And, it's so nice to not even have to smoke it anymore.....edibles, drinkables.....lollipops & other candy. I've never tried them myself, but sure would love to. Now, this is an industry I could get behind....or in front of! With nursing homes full of people on MMJ, employees would be lining up to work there I would think. A better, healthier, happier society.

Jeanne R (1203)
Thursday August 22, 2013, 5:29 pm
What more is needed before it's legalized? Will someone (a politician) ever be courageous enough to work on legalization or are political careers more important than helping so many people?

Freya H (357)
Thursday August 22, 2013, 7:17 pm
Just one more reason to legalize Weed!

Laurie H (817)
Thursday August 22, 2013, 7:17 pm
Very encouraging news Kit, Thank you & we need to hear more & more. Yes=It's great to post again everyone!!!~

Past Member (0)
Thursday August 22, 2013, 9:23 pm
How much longer will we allow the Prohibitionists to control our healthcare destiny? How much longer will we let the DEA, the Drug EMPLOYMENT Administration, stand in the way of the research of this miracle medicine?

"We have been terribly and systematically misled for nearly 70 years in the United States, and I apologize for my own role in that." - Dr. Sanjay Gupta

Thank you so much Kit for the information.

Past Member (0)
Thursday August 22, 2013, 11:02 pm
New Orleans Police Officer Jailed for 2012 Drug War Killing

'Colclough was part of a police team that raided a Gentilly home in March 2012 as part of a marijuana investigation.'

Marijuana must be investigation for its medical properties , not as a justification for murder.

Past Member (0)
Friday August 23, 2013, 12:37 am
Interesting research. Look from where hope can pop...

Sherri G (128)
Friday August 23, 2013, 12:47 am
TY Kit for posting. I hope some narrow minded fools read these articles and learn the many medicinal benefits to marijuana especially for Alzheimers.

Kit B (276)
Friday August 23, 2013, 6:27 am

Cannabinoids are not THC these are two different chemical reactions within the plant.

Cannabinoid -- Cannabinoids are a class of diverse chemical compounds that activate cannabinoid receptors on cells that repress neurotransmitter release in the brain.

Cannabinoids work with or with out the addition of THC, current studies with cancer show the cannabinoids isolate a cancer cell and block the blood supply, killing the cancer cell, while not affecting healthy tissues..

If we see Marijuana as nothing more than an alternative to alcohol then of course tax it, but if we are genuinely interested in the use of Marijuana as a medicine, then do not tax it. Taxing Marijuana presents many enforcement and regulation headaches. It implies that we do not see the plant for all of it's varied uses but only for it's entertainment value, that would be a shame.

Kit B (276)
Friday August 23, 2013, 6:28 am

Thank you MJ for sending me these articles, you made these submissions possible.

Past Member (0)
Friday August 23, 2013, 9:22 am
I, for one, want to see the phrase 'recreational ' ended in regard to cannabis. I use the herb to prevent cancer, not for a fun time. I use the plant to reduce inflammation from arthritis, not for entertainment purposes. I use the all natural substance to reduce the pain from herniated disks and migraine headaches, not for 'recreation'.

Jill Vickerman (416)
Friday August 23, 2013, 11:13 am
The only problem i haved with this is that they used animals to test it on and i dont agree with that...its not fair. I am sure that marijuana is a blessed herb that is good for a lot of ailments, it would not be growing here if it wasnt of any use. it wouldnt surprise me if the medical or pharmacutical industry doesnt want it legalized because they make alot of money out of their own medicines...if everyone switched to Cannibis, they wouldnt make their millions every day.
Just like all homeopathic remedys!

Jo S (619)
Friday August 23, 2013, 12:38 pm
This is getting very exciting now. They really have no reason not to legalize it for many reasons!
Noted & shared.
Thanks again Kit.

Kit B (276)
Friday August 23, 2013, 12:45 pm

Israel has been studying Marijuana for at least 30 years, so if someone says there is no medical benefit, have them check the detailed records from Israel. Even the US has been testing and studying POT and the US owns the patents on cannbanoids. I suggest that is not because they find the plant to be worth less.

Yvonne White (229)
Friday August 23, 2013, 3:34 pm
Exactly Kit!:)

lee e (114)
Saturday August 24, 2013, 7:12 am
Thanks for all the comments funny and otherwise - MJM - thanks for making such a contribution, I use it for both recreational use, when I can, and for the control of my arthritis.
Thanks for posting Kit!
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