Start A Petition

Possible Markers for Mental Illness


Science & Tech  (tags: humans, mental illness, dopamine D2 receptor, DRD2, antipsychotic drugs, protein )

Eduardo
- 3818 days ago - dentalplans.com
Researchers found the differences in the gene for a molecule called the dopamine D2 receptor (DRD2), a protein present on brain cells that are sensitive to the neurotransmitter dopamine. Most antipsychotic drugs work in part by blocking this protein.



Select names from your address book   |   Help
   

We hate spam. We do not sell or share the email addresses you provide.

Comments

Eduardo L (101)
Thursday December 6, 2007, 8:57 pm
Comparisons of these DRD2 genes to the rest revealed three small differences in the DNA called single-nucleotide polymorphisms, or SNPs. Particular changes in two of the SNPs alters how the messenger RNA for DRD2 is processed.

That, in turn, changed the relative amounts of two variants of the protein that are made by the gene.

“The two variants of DRD2 have distinct functions, facilitating or inhibiting dopaminergic transmission, so that a change in their ratios is potentially critical."

”This change would enhance dopamine activity in the brain.”
 
Or, log in with your
Facebook account:
Please add your comment: (plain text only please. Allowable HTML: <a>)


Track Comments: Notify me with a personal message when other people comment on this story


Loading Noted By...Please Wait

 


butterfly credits on the news network

  • credits for vetting a newly submitted story
  • credits for vetting any other story
  • credits for leaving a comment
learn more

Most Active Today in Science & Tech





 
Content and comments expressed here are the opinions of Care2 users and not necessarily that of Care2.com or its affiliates.

New to Care2? Start Here.