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As Drug Industry's Influence Over Research Grows, So Does Potential For Bias

Health & Wellness  (tags: abuse, babies, cancer, children, diet, disease, drugs, ethics, government, health, humans, illness, interesting, investigation, medicine, news, protection, research, risks, safety, study, treatment, warning )

- 1970 days ago -
Over a decade, controversies over blockbuster drugs such as Vioxx, Avandia and Celebrex have erupted amid charges that drug companies had shaped their research to obscure the dangerous side effects.

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Kenneth L (314)
Thursday November 29, 2012, 6:47 am
Avandia was a diabetes drug marketed by GlaxoSmithKline drug giant a few years ago and finally taken off the market. Why? It caused 83,000 heart attacks and deaths. How could it have gotten approved by the FDA in the first place?

"If you looked closely at the data that was out there, you could see warning signs,” said Steven E. Nissen, a Cleveland Clinic cardiologist who issued one of the earliest warnings about the drug. “But they were overlooked.”
A Food and Drug Administration scientist later estimated that the drug had been associated with 83,000 heart attacks and deaths"

Teresa W (782)
Thursday November 29, 2012, 7:19 am
thank you

Nancy M (197)
Thursday November 29, 2012, 9:15 am
"What only careful readers of the article would have gleaned is the extent of the financial connections between the drugmaker and the research. The trial had been funded by GlaxoSmithKline, and each of the 11 authors had received money from the company. Four were employees and held company stock. The other seven were academic experts who had received grants or consultant fees from the firm."

That is bad news. It surprises me as so many scientific journals now require discosures of any potential "conflict".

Elizabeth Fuller (134)
Thursday November 29, 2012, 9:59 am
Yes, and it's even sadder when pharmaceutical company marketers walk into your Dr's office with free samples of the stuff to give out to unsuspecting patients.

Kenneth L (314)
Thursday November 29, 2012, 2:36 pm
Thanks Ellen, somehow I have to learn how to send a clickable link...somebody must've done it for me, thanks. I'm kind of surprised people are surprised or don't know this stuff regarding 'Big Pharma. I mean, anywhere, anytime, there are billions of dollars involved, how could anybody think humans won't be profiting unethically in some way shape or form? And yes this includes 'health'.

Gloria picchetti (304)
Thursday November 29, 2012, 4:15 pm
I think the drugs are worse than the diseases. Just make pot legal so we can die in peace.

Jae A (316)
Thursday November 29, 2012, 6:54 pm
Ditto Kenneth...Ditto Gloria..Ditto Ellen Ditto Carmen...Ditto Nancy...and Yes Elizabeth the doc's are still the legal drug pushers with samples to hand out which street dealers don't even do to any reg./large degree...not that I've heard about .

Jae A (316)
Thursday November 29, 2012, 7:09 pm
I don't see how anyone can take the ones they advertise on tv...most of which their side effects are worse than why one is to take them. Are people that hooked on the words of a 'doc' that they go to such insane degrees with taking whatever one prescribes..........

Roseann d (178)
Thursday November 29, 2012, 10:24 pm
With so many GMO-based pharmaceuticals, that in itself negates me taking them, I'd have to know the ingredients and sources to ensure it was GMO-Free. Last I checked, that was patent-protected proprietary info.and drs really have no idea that level of detail. Besides, Kaiser-Permanente just formally announced GMOs are I don't see how something that causes organ damage has health benefits.

Roseann d (178)
Thursday November 29, 2012, 10:28 pm
Advertising prescription drugs is downright unethical.

Past Member (0)
Thursday November 29, 2012, 10:47 pm
Where are the ethics in the drug industry?!

Kenneth L (314)
Friday November 30, 2012, 1:24 am
I think the U.S. is the only country in the world (besides New Zealand?) that allows drug advertising on tv.

(Drug Ads On Television; How Did It Happen?)

"Vioxx was popularized mainly by the image of Dorothy Hamill lacing up her skates and gliding over the ice despite her osteoarthritis, all because of Vioxx. Merck had to take Vioxx off the market because even while the commercials were running, they were receiving alarming reports that the millions of patients who responded to the ad and demanded their doctors prescribe Vioxx were risking stroke or serious heart problems".

P A (117)
Friday November 30, 2012, 3:03 am
Thanks Kenneth - it really is horrifying what the drug companies get up to - there seem to be many more casualties in their wake than in major wars! 83,000 deaths from just one product - HELP!!!

Teresa Cowley (274)
Friday November 30, 2012, 3:07 am
My father's generation (at least, my mother and father) believed totally and completely in Doctors--their word was law, truth, always to be believed. I cannot tell you how it ruined my mother's life and health, and the childhood of two of their children.
Doctor's lie--alot of doctors lie alot! I almost never find one I trust--needless to say, I rarely go to doctors, don't have a family doctor, and don't take prescription meds.
My mother spent most of her week, months, years, life going from one doctor to another--for various problems--took an untold number of pills (most were psychoactive or pain-killers)--she was ill for about forty years--then her main doctor died and she got well.
People need to learn to read, research, question "authority"--Big Pharma exists for Big Pharma (inclusive of doctors, researchers, pharmacists, poiticians, etc)--they don't care about our health--or giving us a good quality of life--we must do that for ourselves.

Teresa Cowley (274)
Friday November 30, 2012, 4:03 am
Kenneth, This is completely off the subject, but it's also the only way I can get a message to anyone.
My messaging does not work--I can write any message I want (initiate a message or respond to one) but I have no reply button, so I can't send it out.
Also, I can read and respond to the different posts (such as here and now), but I cannot access any comments except those on the first page--the line allowing access to the older comments ("to older comments" or something like that)is completely missing.
Could you please ask someone at tech support (or whereever) to look into this? I would certainly appreciate it.
I tried to send a message through the "Care2 Problems" Board, but again, I have no reply button for that either (the button exists, but it is dead).
Sorry to put this message through here, but I knew of no other way to send it--it's like being mute in a blind world, sort of.
Thank you, Kenneth.

Kenneth L (314)
Friday November 30, 2012, 5:10 am
Sure, no problem Theresa, I have posted it in F&S Feedback and Suggestions Group run by Eric, and either he or someone else will solve it, and I will then forward it to could join that group or read the solutions they put up for it on the thread called 'Site problems----etc.'

Btw, your first post was SPOT ON, you put it all in a nutshell.

Past Member (0)
Friday November 30, 2012, 5:32 am
Noted. Thanks.

Roseann d (178)
Friday November 30, 2012, 5:41 am
Exploiting I'll health for profit like our cuurent system that turns I'll health into a commodity is a sick system. We should have Universal Healthcare, singlepayer all the way. Me, I'll continue to stay clear of doctors and drugs. I'll opt for holistic, homeopathic, and alternative therapies. My neighbor was always spunky and full of life until she had chemo and radiation, now she can barely climb stairs and she is not the same at all. Ive lost my cousin and a friend to chemo related issues, not to camcer. It just makes no sense to poison a body to heal it. Sounds like some dark ages, Medieval treatment.

Nancy M (197)
Friday November 30, 2012, 6:06 am
I agree with advertising drugs being illegal.

Samples? if we accept that SOME drugs are legitimate (i.e. antibiotics for infections?), then doctors frequently hand those samples out to the people without insurance knowing that they would not be able to afford to buy it. Works at least for medicines one takes for short term problems such as the aforementioned infection. I have no problem with that use of samples.

Michael Barth (43)
Friday November 30, 2012, 11:40 am

S G (29)
Friday November 30, 2012, 6:12 pm

reft h (66)
Saturday December 1, 2012, 12:45 am
thanks for the article

M B (62)
Saturday December 1, 2012, 2:23 pm
Thank you, Kenneth.

Past Member (0)
Saturday December 1, 2012, 11:24 pm
The drug industry's influence over research means it will not publish or take note of anything it find which it does not like. And so more disasters like thalidomide will follow. Only neutral bodies should make decisions.

Karen R (87)
Sunday December 2, 2012, 8:00 am
too much power in the wrong hands as usual

Judith Green (8)
Sunday December 2, 2012, 3:02 pm
Noted and shared on FB. Thanks for posting. We need to spread awareness about this issue.

Mary D (47)
Sunday December 2, 2012, 9:36 pm
Thanks Kenneth.

Carlene V (202)
Monday December 3, 2012, 6:01 am
Thanks Kenneth. Very interesting to note. I also think they should not allow drug companies to advertise on television or radio. Would be interestng to know how much more a drug costs when the company figures in it's advertising costs and puts it on the consumer.

Devon Leonard (54)
Thursday December 6, 2012, 9:41 am
Thanx Kenneth. These updates need to be put out there again and again.... Perhaps someday Naturopathic and Homeopathic medicines will be accepted and covered by insurance plans along with acupuncture as well. When my mother had cancer it was her weekly acupuncture sessions that relieved her pain more than anything.
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