Silver: Bad for Bacteria, Not Just Vampires

In medicine, it seems like we’re always looking for a silver bullet — the treatment to end all treatments, the thing that will provide definitive care for patients struggling with infections, diseases and other health problems. While real silver bullets in medicine don’t exist, because no treatment can be 100% reliable, researchers have found something pretty close, and it’s literally made out of silver. It’s also quite ancient, a treatment with a history dating back to Ancient Greece and Rome.

Bacterial infections are notoriously tough to treat, because there are so many bacterial species and they all work in different ways in the body. That goes double for so-called Gram-negative bacteria, which have a doubled cell membrane, making it hard for antibiotic medications to penetrate them and do their work. Scientists have been developing and experimenting with an array of antibiotic medications for decades, and they’re constantly forced to keep researching because bacteria keep evolving to foil their efforts.

Which is why researchers got curious about silver, a metal historically used in the treatment of bacterial infections. While they were aware that the metal seemed to have some antimicrobial effects, they wanted to learn more about how it worked, and about the potential limitations — the problem with silver is that if patients receive too high a dose, they can start experiencing complications, including a condition that permanently discolors their skin. What they found is that while silver alone may not be enough to kill off an infection, when silver and antibiotics are teamed up, they can sometimes lick a tough infection.

Here’s how it works: antibiotics function by producing toxins that lead to cell death, but in order to be effective, they have to be able to penetrate the cell first. Silver bonds to sulfur, an important component of proteins, and makes it impossible for those proteins to fold correctly, so they can’t do what they’re supposed to do, like, say, creating a cell membrane. Consequently, the silver creates openings for the antibiotics to get inside and start interfering with the function of bacterial cells.

It does more than that, though. It interferes with the way bacteria use iron, a critical metal, and it also forces bacterial cells to start producing reactive oxygen species, which damage the cell. Imagine firing a bullet inside a crowded room: that’s what silver does to bacteria, ricocheting around to create chaos. The fact that it makes cells more susceptible to antibiotics allows doctors to use less, which reduces the risk of side effects for the patients. It also reduces antibiotic resistance, making formerly resistant infections vulnerable to treatment again.

Thanks to the one-two punch, the patient doesn’t need to take high doses of silver or antibiotics, and thus runs a much lower risk of side effects. And her infection is more likely to respond quickly, with the antibiotics capable of killing tens to thousands more bacteria than they would on their own.

This approach to treatment still needs some more research before it can be rolled out on a large scale, to make sure it’s safe and effective, but this is a good start in an often frustrating area of research. As the world’s population grows and antibiotic use increases, more and more antibiotic-resistant infections are arising, and they’re spreading like wildfire through hospitals and other health care facilities. The more tools we have in our arsenal, the better, especially for immunocompromised patients who aren’t able to fight such infections effectively on their own, and thus are at a higher risk of death and severe complications.

Photo credit: Thinkstock


Spirit Spider
Spirit Spider4 years ago

Thank you :-)

GGma Sheila D.
GGmaSheila D4 years ago

Let me know when it comes out in pill form...

Ernie Miller
william Miller4 years ago


irene fernandez
irene Fernandez4 years ago

My sister has been drinking colloidal silver (1 tbs to 1 lt of water) as her regular water for a few weeks now. Last week she got a cold and it lasted much less than regular.
Do you recommend she gargle it straight?

JL A4 years ago

sounds promising if other cells aren't similarly affected

Colleen Maranda
Colleen B4 years ago

Fungal infection? E.g., toenails? Coconut Oil / Butter. More affordable than dairy butter. Pure and natural. Also helps your brain and Alzheimer's. For a safer, affordable chest rub (including for babies), mix with few drops lavender and eucalyptus oils. For facial acne, mix with few drops organic Tea Tree Oil. In a hot climate? - store in the 'fridge to keep it solid. See YouTube.

Maria M.
Maria Maugeri4 years ago

A good friend suggested I use colloidal silver as a gargle for sore throat and ever since then it's the only thing I need! Amazing stuff, within a day the throat is back to normal. I also used it as a spray on toenails with fungus - I had tried for years to get rid of the fungus with expensive and nasty lotions - but only after a couple of months of colloidal silver I have normal toe nails. Others I have told about this treatment confirm it has worked for them.

Colleen Maranda
Colleen B4 years ago

I agree with Leah S., that Colloidal Silver does not need their manufactured toxin (ANTI-biotic). This research would be funded by the mega billion dollar, CORRUPTED pharma Industry. Their business is to keep people alive but sick, so they hold their place as Nbr 2 after BigOil. This is how they easily bribe politicians to keep people ignorant and also restrict our access to the safer, affordable, natural remedies - which they tried to patent but were denied.

See article: "The Borax Conspiracy: how the arthritis cure has been stopped", by Walter Last.

Also, the website of Dr Carolyn Dean MD ND.

Jessica Larsen
Janne O4 years ago

Interesting, but you need to fix the title. As a horror fan I have to point out that vampires can take silver just fine, it's werewolves who have a problem with it.

John B.
John B4 years ago

Thanks Ms. Smith for the exceptionally informative article!